Cutting-Edge Hydrogels: Carboxymethyl Hyaluronic Acid for Medical Advances

Wazzup Pilipinas!?

In a world increasingly being aware of the environmental footprint of industrial processes and products, the quest for sustainable solutions has become paramount. Fortunately, we have come to see a groundbreaking invention – the Carboxymethyl Hyaluronic Acid (CMHA) Hydrogels, a true game-changer in diverse sectors ranging from healthcare to textiles. This invention was created in the busy laboratories of the Philippine Nuclear Research Institute of the Department of Science and Technology (DOST-PNRI). 

The Invention

CMHA Hydrogels are derived from hyaluronic acid, a compound renowned for its multifaceted biological functions, including promoting cell migration and proliferation. In general, hydrogels are materials that can hold large amounts of water in their 3-dimensional structure. This ability to retain water makes hydrogels unique and useful for various applications. What sets CMHA apart is its production process, which eschews toxic agents in favor of a green approach utilizing only water and radiation. This not only ensures a high-purity product but also underscores its eco-friendly credentials. For instance, it can provide a moist environment around the wound and support the healing process.

CMHA hydrogels were created using green technology which means that they are prepared without chemical additives and at ambient temperature. They are derived from hyaluronic acid which has diverse biological functions and the addition of the carboxymethyl group imparts additional functionalities. Without toxic crosslinking agents, our hydrogels exhibit exceptional biocompatibility. “Before we can prepare the hydrogel, we have to synthesize CMHA since it is not commercially available. Scaling up the synthesis of CMHA is not easy – the purification and drying steps are tedious and long because we do not have the needed equipment. We were able to do it with tenacity and patience”, said Ms. Relleve when once asked about the struggles and challenges they faced during the development of their invention.

Versatility and Advantages

One of the most remarkable aspects of CMHA Hydrogels is its versatility. With properties adjustable via irradiation dose, these hydrogels exhibit a wide range of swelling capabilities,making them ideal for various biomedical applications. From wound dressings to ocular treatments and drug delivery systems, CMHA Hydrogels offer a safe, biocompatible alternative to conventional products, free from toxic residues.

The competitive advantage of CMHA Hydrogels lies in its carboxymethyl group, which enhances hydrophilicity and water-absorbing capacity. This, coupled with its biodegradability and stimuli-responsive swelling properties, positions CMHA Hydrogels as a frontrunner in sustainable material innovation. Moreover, its exceptional safety profile makes it a preferred choice across industries, from pharmaceuticals to cosmetics and beyond.

The Creators

The journey from concept to reality has been fueled by the relentless dedication of the PNRI team, led by inventors Lorna S. Relleve, Alvin Kier R. Gallardo, Mariel G. Tecson, Lucille V. Abad, and John Andrew A. Luna. Their vision, coupled with PNRI's commitment to advancing nuclear science for peaceful applications, has culminated in a groundbreaking invention poised to leave an indelible mark on the global stage.

“We want to develop hydrogels by radiation technology that has superior quality and can be used safely in various applications that can enhance the quality of life,” said Ms. Relleve when asked what inspired them to develop this invention.

“We are motivated by the opportunity to bring our vision to life and make meaningful contributions in the field of radiation processing and to make a difference in the world,” she added.

Ms. Relleve, who has been with the DOST-PNRI for three decades, spearheaded the research and development of the CMHA Hydrogels. She has always been fond of polymer modification through radiation, especially for various hydrogel applications. She, together with her team believes that success is when they can publish their work to have it patented, and eventually commercialize.

Commercial Vision

As the global Hydrogel Market continues to expand, with projections reaching USD 32.62 billion by 2029, the potential for CMHA Hydrogels is immense. From apparel and home textiles to industrial applications, the demand for sustainable materials is on the rise, presenting a lucrative opportunity for innovators and investors alike.

The CMHA Hydrogels epitomize the marriage of innovation and sustainability, paving the way for a greener, healthier future. With its myriad applications and untapped potential, this invention stands as a testament to the power of scientific ingenuity in addressing pressing global challenges. As of now, the CMHA Hydrogels have not been deployed yet, but prototypes are available. However, further research and development works are needed to use them in various medical applications.

As we embark on a journey towards a more sustainable world, CMHA Hydrogels serve as a beacon of hope, inspiring us to push the boundaries of what is possible and usher in a new era of responsible innovation.

** This feature is a part of the "Shape the Future" campaign, highlighting nine Philippine inventions featured in the 49th International Exhibition of Inventions Geneva (IEIG) on April 17-21, 2023. Competing for gold awards, these innovations also aim to promote local technologies for potential international technology transfer and commercialization.

By Matt Jerome Casequin

Naturally Enhanced Textiles: Blended Yarns with Organic Fiber

Wazzup Pilipinas!?

In the buzzing laboratories of the Department of Science and Technology - Philippine Textile Research Institute (DOST-PTRI), a group of visionary minds led by Mr. Ronald Pechera, Mr. Karl Marx Lennin Florante, Mr. Emmanuel Victor Buniao, Mr. Noriel Sorsone, Mr. Jenneli Caya, and Dr. Julius Leaño, Jr. has embarked on a journey to reshape the textile industry. Their Invention? The Lyocell or Natural Fiber-Blended Yarns, a sustainable substitute aims to transform the way we think about textiles.

The European Parliament has published an article on the environmental impact of textile production and waste. According to the article, it takes a significant amount of water and land to grow cotton and other fibers used in textile production. An estimated 2,700 liters of fresh water are required to produce a single cotton t-shirt, which is equivalent to the amount of drinking water one person would need for 2.5 years.

Identified as the third biggest contributor to water pollution and land use in the year 2020, the textile industry, it consumed an average of nine cubic meters of water, 400 square meters of land, and 391 kilograms of raw materials to produce clothes and shoes for every citizen in the European Union.

When we wash synthetic clothing and fabrics, it can lead to the release of over half a million tonnes of microplastics into the ocean every year. This is a significant global issue. Furthermore, the production of garments can generate pollution that causes harm to the health of local people, animals, and ecosystems where the factories operate. It's a devastating problem that requires immediate attention.

As per the European Environment Agency, the textile purchases made in the European Union in the year 2020 produced around 270 kg of CO2 emissions per individual. This means that the greenhouse gas emissions generated by textile products consumed in the EU amounted to 121 million tonnes.

Lastly, the fashion industry is responsible for approximately 10% of the global carbon emissions, which is more than the combined emissions of international flights and maritime shipping.

Quality and Sustainability

At the core of this innovative approach lies a meticulously refined process designed to transform pineapple leaf fiber, banana fiber, and abaca fiber into a spinnable form. This process constitutes a pivotal step in the production of yarn. Different from conventional methods, this technology overstates a closed-loop system, lessening water utilization by 20 percent and reducing environmental effects by reusing non-toxic solvents.

Lyocell isn't just environmentally friendly, it's also renowned for its superior quality and durability. As compared to synthetic fibers like polyester and rayon, Lyocell offers a decreased carbon footprint and enhanced durability, surpassing even natural fibers like cotton and viscose.

Lyocell fabric is incredibly strong, whether it is wet or dry, and it is more resistant to pilling than cotton. Textile manufacturers appreciate that it is easy to combine this fabric with other types of textiles. For example, it pairs well with cotton, silk, rayon, polyester, nylon, and wool.

Utilization and Impact

The Department of Science and Technology - Philippine Textile Research Institute (DOST-PTRI) has been actively collaborating and forging partnerships with textile manufacturers and handloom weaving communities all across the Philippines in order to bring their vision of sustainable textile production to fruition. Through their tireless efforts, they have succeeded in creating a range of high-quality fabrics that have been transformed into stunning garments and home textiles by talented local and native fashion designers. As a result of their dedication to sustainability and innovation, these textiles have gained widespread recognition both locally and globally, serving as a shining example of the immense potential that sustainable textiles hold in today's fashion industry. 

Market Potential and Future Vision

With the European textile garment market projected to reach USD 256,144.90 million by 2030, there's a growing demand for eco-conscious alternatives among consumers. Lyocell's superior quality and sustainability position it as a frontrunner in the international textile market, especially as European shoppers increasingly favor sustainable and economical fashion.

For the PTRI alliance, putting forward their innovation to market is about more than commercial success. It's about revolutionizing the textile industry and reshaping the whole landscape surrounding production and consumption. Focusing on the perspective of sustainability, innovation, and inclusivity, they aim to create a future where textiles play a central role in framing a more equitable and regenerative world.

Lyocell and Natural Fiber-Blended Yarns are not just a technological breakthrough but a ray of hope for a more sustainable future. These yarns have superior quality, reduced environmental impact, and promising market potential, making them poised to revolutionize the textile industry. They are paving the way for a greener, more sustainable tomorrow, and it's exciting to see the positive impact they'll have on our planet.

** This feature is a part of the "Shape the Future" campaign, highlighting nine Philippine inventions featured in the 49th International Exhibition of Inventions Geneva (IEIG) on April 17-21, 2023. Competing for gold awards, these innovations also aim to promote local technologies for potential international technology transfer and commercialization.

By Matt Jerome Casequin

Photos Courtesy: DOST-Philippine Textile Research Institute

Harnessing the Potentials of Bamboo Textiles

Wazzup Pilipinas!?

In today's rapidly evolving world, where sustainability and environmental consciousness reign supreme, a groundbreaking innovation emerges, promising to revolutionize the textile industry. 

Introducing the Spinnable Lignocellulosic Bamboo Textile from Bambusa philippinensis, a true game-changer crafted by the ingenious minds at the Philippine Textile Research Institute (PTRI), under the Department of Science and Technology (DOST). Spearheaded by inventors Jared Vincent Lacaran, Josanelle Angela Bilo, and Dr. Julius Leaño, Jr., this innovation represents a significant leap toward sustainable and eco-friendly textile production.

According to the Spring Open’s journal on Bamboo as a renewable textile fiber, Bamboo plants are found in almost all parts of the world except those places having extremely cold climates like Europe though some species can be successfully introduced in mild temperate zones, making it more accessible to the textile industry globally.

The Technology

At its core, this technology embodies the essence of sustainability. Leveraging a distinct bamboo variety, the process ensures an eco-friendly production cycle, meticulously crafted to minimize environmental impact. What sets it apart is not just its utilization of bamboo, a highly renewable resource, but also its innovative approach to recycling chemical waste, drastically reducing both waste material and environmental footprint.

(Bamboo Fibers) Photo Courtesy: DOST- Philippine Textile Research Institute

In their desire to maximize the potential of local bamboo as a vast natural resource, the DOST- PTRI promotes its bamboo textile processing technology to produce natural blended yarns and woven fabrics. Noting that bamboo has the highest textile fiber yield among other textile fibers like pineapple, banana, or abaca, more significant opportunities will be provided for income generation from upstream to downstream for the natural textile industry sector. The institute’s technology has been optimized following mechano-chemical processes and has given a significant increase in the value of the bamboo pole to its transformation into bamboo textile fibers (BTF) in a spinnable form to spun yarns.

Competitive Advantage

The competitive advantage of this bamboo-based textile is undeniable. With exceptional tensile strength, it proves its mettle across various textile applications, offering durability that withstands repeated use and washing. Furthermore, its inherent antibacterial and antifungal properties provide a natural shield against harmful microorganisms, catering to the health-conscious consumer base. Moreover, the rapid growth of bamboo without the need for pesticides or fertilizers makes it an attractive option for environmentally-conscious consumers seeking sustainable alternatives. Its versatility in blending with other fibers like cotton, wool, or synthetic fibers expands its applications, while its thermal-regulating properties ensure comfort in diverse climates.

It is also notable that the developed process is community-centric and sustainable in converting poles to textiles, the processing being one other than the regeneration route popularly known as the viscose process, an open system known to affect the environment adversely. Diversifying and expanding bamboo use through sustainable textile processing is a step to mainstreaming bamboo as a natural textile. 

Utilization and Market Potential

The utilization and results of this technology speak volumes. Through exhibitions and fashion shows, DOST-PTRI has successfully heightened public awareness about the immense potential of bamboo, showcasing tangible outputs that captivate the imagination. Establishing partnerships with regional stakeholders through the Bamboo Textile Fiber Innovation Hub further amplifies its impact, paving the way for widespread adoption.

In the market landscape, bamboo textiles have captured the attention of European consumers,driven by their eco-friendly properties and sustainability. The demand for sustainable textiles has propelled the popularity of bamboo-based fabrics, offering softness, breathability, and moisture-wicking properties ideal for various clothing applications. However, concerns linger regarding the environmental impact of conventional bamboo textile production methods. Herein lies the significance of PTRI's innovation, offering a sustainable alternative that aligns with regulatory frameworks and consumer expectations.

What We Look Forward

Looking ahead, the vision for bringing this invention to the global market is ambitious yet attainable. It envisions a paradigm shift in consumer consciousness, where sustainability and ethical production practices take center stage. By empowering farmers and weavers while revolutionizing textile production, this technology heralds a new era of eco-friendly innovation.

The Spinnable Lignocellulosic Bamboo Textile stands as a beacon of hope in an industry grappling with sustainability challenges. With PTRI's unwavering dedication and visionary approach, this innovation holds the key to a more sustainable and vibrant future for the textile industry. As the world embraces the ethos of sustainability, let us embark on this transformative journey towards a greener, more resilient tomorrow. ** This feature is a part of the "Shape the Future" campaign, highlighting nine Philippine inventions featured in the 49th International Exhibition of Inventions Geneva (IEIG) on April 17-21, 2023. Competing for gold awards, these innovations also aim to promote local technologies for potential international technology transfer and commercialization.

By Matt Jerome Casequin

Photos Courtesy: DOST- Philippine Textile Research Institute